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TECHNIQUES

PICSI – Hyaluron Sperm Selection

At Pedieos IVF Center in Cyprus, we offer PICSI Hyaluron Sperm Selection to identify mature, DNA-intact sperm for improved fertilisation and pregnancy results.

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Selection of Mature Sperm

Only fully developed sperm capable of natural fertilisation are chosen.

Higher DNA Integrity

Improves embryo quality by selecting sperm with minimal DNA damage.

Better Outcomes for IVF Patients

Recommended for patients with previous IVF failures or recurrent miscarriages.

About the technique

In traditional ICSI, sperm are chosen mainly based on appearance. However, some morphologically normal sperm may still have DNA damage that can affect embryo quality. PICSI (Physiological ICSI) takes selection a step further by mimicking the natural fertilisation process — it identifies sperm that can bind to hyaluronan, a natural substance surrounding the egg.

This binding ability indicates sperm maturity, normal structure, and intact DNA integrity. At Pedieos IVF Center in Cyprus, this technique helps ensure that only the healthiest sperm are used for fertilisation, reducing the likelihood of chromosomal abnormalities and improving embryo development and pregnancy outcomes.

Fertility specialist consulting couple about PICSI Hyaluron Sperm Selection in Cyprus

Is PICSI right for you?

PICSI Hyaluron Sperm Selection in Cyprus is ideal for couples facing repeated IVF or ICSI failures, or those seeking higher sperm DNA integrity and better embryo quality.

Patients with previous failed IVF or ICSI cycles

Couples who have experienced recurrent miscarriages

Cases with poor embryo development or low-quality embryos

Men with high DNA fragmentation or abnormal sperm parameters

Couples wishing to optimise embryo quality and pregnancy success

How PICSI Works

The PICSI procedure in Cyprus follows a scientific process designed to select only mature, high-quality sperm that bind to hyaluronan for improved embryo outcomes.

Sperm Preparation

Sperm sample is processed and prepared in the laboratory.

Hyaluron Binding Test

The sperm are placed in a special dish coated with hyaluron.

Selection of Mature Sperm

Only sperm that successfully bind to hyaluronan (showing maturity and good DNA) are selected.

ICSI
Procedure

The selected sperm are injected into the eggs using the ICSI technique.

Embryo Development

Fertilised eggs are cultured, and the healthiest embryos are chosen for transfer.

Frequently asked Questions

What is the difference between ICSI and PICSI?
PICSI is an enhanced version of ICSI that selects sperm based on their ability to bind with hyaluronan, ensuring better sperm quality and DNA integrity.
Does PICSI improve pregnancy rates?
Yes, in selected cases, PICSI can lead to higher fertilisation quality and improved embryo development, especially for couples with previous IVF or ICSI failures.
Is PICSI right for every couple?
Not necessarily. Your fertility specialist will recommend PICSI based on sperm quality, previous treatment outcomes, and overall fertility history.
Doctor reviewing PICSI Hyaluron sperm selection results with IVF patient at Pedieos IVF Center Cyprus